Computational aided mechanistic understanding ofCamellia sinensisbioactive compounds against co‐chaperone p23 as potential anticancer agent

Volume: 120, Issue: 11, Pages: 19064 - 19075
Published: Jun 30, 2019
Abstract
Co‐chaperon p23 has been well established as molecular chaperon for the heat shock protein 90 (Hsp90) that further leads to immorality in cancer cells by providing defense against Hsp90 inhibitors, and as stimulating agent for generating overexpressed antiapoptotic proteins, that is, Hsp70 and Hsp27. The natural compounds such as catechins from Camellia sinensis (green tea) are also well known for inhibition activity against various cancer....
Paper Details
Title
Computational aided mechanistic understanding ofCamellia sinensisbioactive compounds against co‐chaperone p23 as potential anticancer agent
Published Date
Jun 30, 2019
Volume
120
Issue
11
Pages
19064 - 19075
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