Review paper
Targeting DNA repair in breast cancer
Abstract
Targeting of DNA repair is an important therapeutic approach in breast cancer, particularly for BRCA1/2 associated breast cancers and those characterized by a “BRCAness” phenotype including those with “triple negative” subtype. Various assays and scores have been developed to evaluate degree of homologous recombination deficiency in the hope that this would aid in predicting for susceptibility to DNA repair targeting agents, and yet, presence of...
Paper Details
Title
Targeting DNA repair in breast cancer
Published Date
Oct 1, 2019
Journal
Volume
47
Pages
33 - 42
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