Early second-trimester plasma cell free DNA levels with subsequent risk of pregnancy complications

To investigate the association between cfDNA levels measured during non-invasive prenatal testing (NIPT) and the risk of pregnancy complications in a Chinese population. This was a retrospective cohort study of 831 pregnant women who underwent NIPT at 12–22 weeks of gestation. Maternal plasma cfDNA levels and pregnancy outcomes were obtained from NIPT Screening System and hospitalization records, respectively. Logistic regression analysis was...