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Clinical Biochemistry
IF
2.43
Papers
9573
Papers 9541
1 page of 955 pages (9,541 results)
Newest
Published on Jul 1, 2019in Clinical Biochemistry 2.43
Jackie Ferguson2
Estimated H-index: 2
(NIBSC: National Institute for Biological Standards and Control),
Dina Patel8
Estimated H-index: 8
(Northern General Hospital)
+ 2 AuthorsChris Burns10
Estimated H-index: 10
(NIBSC: National Institute for Biological Standards and Control)
Abstract Objectives Replacements are required for the WHO International Standards (IS) for free PSA, coded 96/668 and total PSA (90:10), coded 96/670, which were established in 1999 to support efforts to harmonise PSA assays and address non-equimolarity. An important consideration is that the introduction of the replacements should have minimal impact on PSA measurements. Design and methods We report the development of a replacement strategy, informed by field assessment of preparations through ...
Published on Jun 1, 2019in Clinical Biochemistry 2.43
S.L. Curtis1
Estimated H-index: 1
,
B.P. Norman2
Estimated H-index: 2
(University of Liverpool)
+ 4 AuthorsNorman B. Roberts17
Estimated H-index: 17
Abstract Objectives We have assessed the effect of elevated concentrations of hydroxyphenylpyruvic acid (HPPA), hydroxyphenyllactic acid (HPLA) and tyrosine, on a range of chemistry tests in serum and urine to explore the potential for chemical interference on routine laboratory analyses in patients with alkaptonuria (AKU) treated with nitisinone and similarly implications for patients with hypertyrosinemia type1 (HT-1). Materials and methods HPPA, HPLA and tyrosine were added separately to pool...
Published on Jul 1, 2019in Clinical Biochemistry 2.43
Xiaosong Yuan1
Estimated H-index: 1
(Nanjing Medical University),
Lingna Zhou (Nanjing Medical University)+ 3 AuthorsBin Yu5
Estimated H-index: 5
(Nanjing Medical University)
Abstract Objective To investigate the association between cfDNA levels measured during non-invasive prenatal testing (NIPT) and the risk of pregnancy complications in a Chinese population. Methods This was a retrospective cohort study of 831 pregnant women who underwent NIPT at 12–22 weeks of gestation. Maternal plasma cfDNA levels and pregnancy outcomes were obtained from NIPT Screening System and hospitalization records, respectively. Logistic regression analysis was performed to investigate t...
Published on Jun 1, 2019in Clinical Biochemistry 2.43
Thanyaornwanya Charoenwijitkul (KKU: Khon Kaen University), Kritsada Singha4
Estimated H-index: 4
(KKU: Khon Kaen University)
+ 5 AuthorsSupan Fucharoen34
Estimated H-index: 34
(KKU: Khon Kaen University)
Abstract Objective The 3.7 kb deletion (-α 3.7 ) is the most common form of α + -thalassemia found in multiple populations which can be classified into three subtypes. In order not to mis-identify it, the molecular information within each population is required. We have addressed this in northeast Thai and Laos populations. Methods Screening for α + -thalassemia was initially done on 1192 adult Thai subjects. In addition, 77 chromosomes of Thai newborns and 26 chromosomes of Laos with -α 3.7 α +...
Published on Jun 1, 2019in Clinical Biochemistry 2.43
Jon Brynildsen5
Estimated H-index: 5
(University of Oslo),
Peder Myhre4
Estimated H-index: 4
(University of Oslo)
+ 6 AuthorsHelge Røsjø21
Estimated H-index: 21
(University of Oslo)
Abstract Background Secretoneurin (SN) concentrations provide important prognostic information in patients with myocardial dysfunction. Whether preoperative SN concentrations improve risk assessment in patients with moderate to severe aortic stenosis (AS) is unknown. Methods We included 57 patients with moderate to severe AS referred for presurgical evaluation. All patients were examined with comprehensive echocardiography, electrocardiogram (ECG), and biochemical measurements and compared to 10...
Published on Jul 1, 2019in Clinical Biochemistry 2.43
James Derzon2
Estimated H-index: 2
(RTP: Research Triangle Park),
Nicole Clarke + 3 AuthorsRobert L. Thurer23
Estimated H-index: 23
Abstract Objectives To evaluate the effectiveness of antifibrinolytics tranexamic acid (TA), e-aminocaproic acid (EACA), and aprotinin to decrease overuse of red blood cell transfusions in adult surgical and non-surgical patients. Methods This review followed the Centers for Disease Control and Prevention (CDC) Laboratory Medicine Best Practice (LMBP™) Systematic Review (A-6) method. Eligible studies were assessed for evidence of effectiveness of TA or EACA in reducing the number of patients tra...
Published on Jul 1, 2019in Clinical Biochemistry 2.43
Yuanwen Chen1
Estimated H-index: 1
(CAS: Chinese Academy of Sciences),
Nian Wu (CAS: Chinese Academy of Sciences)+ 2 AuthorsChengyi Wu4
Estimated H-index: 4
(CQMU: Chongqing Medical University)
Abstract Background Although the function of microRNA-21 and microRNA-206 in breast cancer cells have been investigated in vitro, their association with estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) are not reported. Methods ER, PR, HER2, and Ki-67 staining pattern were utilized to classify 75 breast cancer patients recruited. The malignancy was predicted with tumor nodes metastases (TNM) classification. RT-qPCR was performed to detect th...
Published on Jul 1, 2019in Clinical Biochemistry 2.43
Valle Recasens1
Estimated H-index: 1
,
Paloma Ropero10
Estimated H-index: 10
(Hospital Clínico San Carlos)
+ 10 AuthorsR. Rubio
Abstract We report two cases of hemoglobin Sendagi in a Romanian family residing in Spain: a four-year-old boy and his mother, who had been previously diagnosed with another type of congenital hemolytic anemia and had undergone splenectomy in her country during childhood. The unstable hemoglobin variant, hemoglobin Sendagi, is characterized by decreased oxygen affinity caused by replacement of one of the critical amino acid residues, phenylalanine beta 42 (CD1) of the beta-chain, with valine in ...
Published on Jul 1, 2019in Clinical Biochemistry 2.43
Peter A. Kavsak25
Estimated H-index: 25
(HHS: Hamilton Health Sciences),
Craig Ainsworth6
Estimated H-index: 6
(HHS: Hamilton Health Sciences)
Published on Jun 1, 2019in Clinical Biochemistry 2.43
Victoria Higgins6
Estimated H-index: 6
(U of T: University of Toronto),
Shervin Asgari , Khosrow Adeli54
Estimated H-index: 54
(U of T: University of Toronto)
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