Original paper

Genetic identification of brain cell types underlying schizophrenia

Volume: 50, Issue: 6, Pages: 825 - 833
Published: May 21, 2018
Abstract
With few exceptions, the marked advances in knowledge about the genetic basis of schizophrenia have not converged on findings that can be confidently used for precise experimental modeling. By applying knowledge of the cellular taxonomy of the brain from single-cell RNA sequencing, we evaluated whether the genomic loci implicated in schizophrenia map onto specific brain cell types. We found that the common-variant genomic results consistently...
Paper Details
Title
Genetic identification of brain cell types underlying schizophrenia
Published Date
May 21, 2018
Volume
50
Issue
6
Pages
825 - 833
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