Impaired Glymphatic Transport in Spontaneously Hypertensive Rats
Abstract
The glymphatic system is a brainwide CSF transport system that uses the perivascular space for fast inflow of CSF. Arterial pulsations are a major driver of glymphatic CSF inflow, and hypertension that causes vascular pathologies, such as arterial stiffening and perivascular alterations, may impede the inflow. We used dynamic contrast-enhanced MRI to assess the effect of hypertension on glymphatic transport kinetics in male young and adult...
Paper Details
Title
Impaired Glymphatic Transport in Spontaneously Hypertensive Rats
Published Date
Jun 17, 2019
Journal
Volume
39
Issue
32
Pages
6365 - 6377
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