SGLT1 is required for the survival of triple‐negative breast cancer cells via potentiation of EGFR activity

Volume: 13, Issue: 9, Pages: 1874 - 1886
Published: Jul 10, 2019
Abstract
Sodium/glucose cotransporter 1 (SGLT1), an essential active glucose transport protein that helps maintain high intracellular glucose levels, was previously shown to interact with epidermal growth factor receptor (EGFR); the SGLT1-EGFR interaction maintains intracellular glucose levels to promote survival of cancer cells. Here, we explore the role of SGLT1 in triple-negative breast cancer (TNBC), which is the most aggressive type of breast...
Paper Details
Title
SGLT1 is required for the survival of triple‐negative breast cancer cells via potentiation of EGFR activity
Published Date
Jul 10, 2019
Volume
13
Issue
9
Pages
1874 - 1886
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