Optogenetics in the Era of Cerebral Organoids

Optogenetics refers to a combination of optical and genetic tools to control the activity of individual neurons and decode brain circuitry. Cerebral organoids derived from human pluripotent stem cells provide new opportunities for studying neurodevelopmental and neurodegenerative diseases in human-like tissue. The optogenetic technique and cerebral organoids can be combined to advance knowledge of the human brain and its related disorders and...