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Hossein Baharvand
University of Science and Culture
482Publications
44H-index
7,529Citations
Publications 494
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#1Maryam Zare-Gachi (UT: University of Tehran)
#2Hamed Daemi (Royan Institute)H-Index: 12
Last.Hossein Baharvand (University of Science and Culture)H-Index: 44
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Abstract Nowadays, considerable effort is made to overcome bacterial diseases and combat bacterial resistance. In this context, development of safe and efficient antimicrobial wound dressings which can selectively fight against the bacteria and decrease disruption of normal cells such as red blood cells in wound bed is highly required. In this study, a series of ammonium salts of alginate were prepared and the role of different counter-cations including sodium, triethylammonium, tributylammonium...
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Abstract Retinal pigment epithelial (RPE) cells are indispensable for eye organogenesis and vision. To realize the therapeutic potential of in vitro-generated RPE cells for cell-replacement therapy of RPE-related retinopathies, molecular mechanisms of RPE specification and maturation need to be investigated. So far, many attempts have been made to decipher the regulatory networks involved in the differentiation of human pluripotent stem cells into RPE cells. Here, we exploited a highly-efficient...
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Mesenchymal stem cells (MSCs) are considered primary candidates for treating complex bone defects in cell-based therapy and tissue engineering. Compared with monolayer cultures, spheroid cultures of MSCs (mesenspheres) are favorable due to their increased potential for differentiation, extracellular matrix (ECM) synthesis, paracrine activity, and in vivo engraftment. Here, we present a microparticle incorporation strategy for fabrication of osteognic microtissues from mesenspheres in a cost-effe...
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#1Maryam Kay (TMU: Tarbiat Modares University)H-Index: 4
#2Bahram Mohammad Soltani (TMU: Tarbiat Modares University)H-Index: 10
Last.Hossein Baharvand (University of Science and Culture)H-Index: 44
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Background WNT and TGFβ signaling pathways play critical regulatory roles in cardiomyocyte fate determination and differentiation. MiRNAs are also known to regulate different biological processes and signaling pathways. Here, we intended to find candidate miRNAs that are involved in cardiac differentiation through regulation of WNT and TGFβ signaling pathways.
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Cardiovascular progenitor cells (CPCs) derived from human pluripotent stem cells (hPSCs) are proposed to be invaluable cell sources for experimental and clinical studies. This wide range of applications necessitates large-scale production of CPCs in an in vitro culture system, which enables both expansion and maintenance of these cells. In this study, we aimed to develop a defined and efficient culture medium that uses signaling factors for large-scale expansion of early CPCs, called cardiogenic...
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Spinal cord injury (SCI) results in glial scar formation and irreversible neuronal loss, which finally leads to functional impairments and long-term disability. Our previous studies have demonstrated that the ectopic expression of Zfp521 reprograms fibroblasts and astrocytes into induced neural stem cells (iNSCs). However, it remains unclear whether treatment with Zfp521 also affects endogenous astrocytes, thus promoting further functional recovery following SCI. Rat astrocytes were transdiffere...
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