Maternal serum metabolome and traffic-related air pollution exposure in pregnancy

Maternal exposure to traffic-related air pollution during pregnancy has been shown to increase the risk of adverse birth outcomes and neurodevelopmental disorders. By utilizing high-resolution metabolomics (HRM), we investigated perturbations of the maternal serum metabolome in response to traffic-related air pollution to identify biological mechanisms. We retrieved stored mid-pregnancy serum samples from 160 mothers who lived in the Central...