Original paper
Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice
Abstract
•Patients with PSC showed increased IFNγ serum concentrations and elevated frequencies of hepatic CD56bright NK cells. •Less hepatic NK cells and CD8+ T cells expressing cytotoxic effector molecules after deletion of IFNγ in Mdr2−/− mice. •Less inflammatory macrophages and more restorative macrophages after genetic deletion of IFNγ. •Genetic deletion and blockage of IFNγ in Mdr2−/− mice attenuated liver fibrosis. Background and Aims Primary...
Paper Details
Title
Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice
Published Date
Oct 1, 2019
Journal
Volume
71
Issue
4
Pages
773 - 782
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History