Review paper
Modeling blood diseases with human induced pluripotent stem cells
Abstract
Induced pluripotent stem cells (iPSCs) are derived from somatic cells through a reprogramming process, which converts them to a pluripotent state, akin to that of embryonic stem cells. Over the past decade, iPSC models have found increasing applications in the study of human diseases, with blood disorders featuring prominently. Here, we discuss methodological aspects pertaining to iPSC generation, hematopoietic differentiation and gene editing,...
Paper Details
Title
Modeling blood diseases with human induced pluripotent stem cells
Published Date
Jun 1, 2019
Journal
Volume
12
Issue
6
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