doi.org/10.1016/j.omtn.2019.05.016
Original paper

Core-Shell Polymer-Based Nanoparticles Deliver miR-155-5p to Endothelial Cells

..., Cédric Chauvierre
18
Molecular Therapy — Nucleic Acids6.50
Volume: 17, Pages: 210 - 222
Published: Sep 1, 2019
Abstract
Heart failure occurs in over 30% of the worldwide population and most commonly originates from cardiovascular diseases such as myocardial infarction. microRNAs (miRNAs) target and silence specific mRNAs, thereby regulating gene expression. Because the endogenous miR-155-5p has been ascribed to vasculoprotection, loading it onto positively charged, core-shell poly(isobutylcyanoacrylate) (PIBCA)-polysaccharide nanoparticles (NPs) was attempted....
Paper Fields
Paper Details
Title
Core-Shell Polymer-Based Nanoparticles Deliver miR-155-5p to Endothelial Cells
DOI
doi.org/10.1016/j.omtn.2019.05.016
Published Date
Sep 1, 2019
Journal
Molecular Therapy — Nucleic Acids
Volume
17
Pages
210 - 222
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