Original paper
The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency
Abstract
Small nucleolar RNA host gene 3 (Snhg3) is a long non-coding RNA (lncRNA) that was shown to participate in the tumorigenesis of certain cancers. However, little is known about its role in embryonic stem cells (ESCs).Here, we investigated the role of Snhg3 in mouse ESCs (mESCs) through both loss-of-function (knockdown) and gain-of-function (overexpression) approaches. Alkaline phosphatase staining, secondary colony formation, propidium iodide...
Paper Details
Title
The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency
Published Date
May 31, 2019
Journal
Volume
10
Issue
1
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Notes
History