Original paper
Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus
Abstract
Epigenetic mechanisms may play a major role in the biological embedding of early-life stress (ELS). One proposed mechanism is that glucocorticoid (GC) release following ELS exposure induces long-lasting alterations in DNA methylation (DNAm) of important regulatory genes of the stress response. Here, we investigate the dynamics of GC-dependent methylation changes in key regulatory regions of the FKBP5 locus in which ELS-associated DNAm changes...
Paper Details
Title
Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus
Published Date
May 23, 2019
Journal
Volume
11
Issue
1
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Notes
History