Original paper
The Translational Landscape of the Human Heart
Abstract
Gene expression in human tissue has primarily been studied on the transcriptional level, largely neglecting translational regulation. Here, we analyze the translatomes of 80 human hearts to identify new translation events and quantify the effect of translational regulation. We show extensive translational control of cardiac gene expression, which is orchestrated in a process-specific manner. Translation downstream of predicted disease-causing...
Paper Details
Title
The Translational Landscape of the Human Heart
Published Date
Jun 1, 2019
Journal
Volume
178
Issue
1
Pages
242 - 260.e29
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Notes
History