An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium
Abstract
A major challenge in myocardial infarction (MI)-related heart failure treatment using microRNA is the efficient and sustainable delivery of miRNAs into myocardium to achieve functional improvement through stimulation of intrinsic myocardial restoration. In this study, we established an in vivo delivery system using polymeric nanoparticles to carry miRNA (miNPs) for localized delivery within a shear-thinning injectable hydrogel. The miNPs...
Paper Details
Title
An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium
Published Date
May 31, 2019
Journal
Volume
13
Issue
9
Pages
9880 - 9894
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