Review paper
Understanding the mechanisms of reversal of type 2 diabetes
Abstract
Clinical and pathophysiological studies have shown type 2 diabetes to be a condition mainly caused by excess, yet reversible, fat accumulation in the liver and pancreas. Within the liver, excess fat worsens hepatic responsiveness to insulin, leading to increased glucose production. Within the pancreas, the β cell seems to enter a survival mode and fails to function because of the fat-induced metabolic stress. Removal of excess fat from these...
Paper Details
Title
Understanding the mechanisms of reversal of type 2 diabetes
Published Date
Sep 1, 2019
Volume
7
Issue
9
Pages
726 - 736
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