Studying the ShcD and ERK interaction under acute oxidative stress conditions in melanoma cells
Volume: 112, Pages: 123 - 133
Published: Jul 1, 2019
Abstract
The newly identified melanoma-associated adaptor ShcD was found to translocate to the nucleus upon hydrogen peroxide treatment. Therefore, the aim of this study was to identify the ShcD network in melanoma cells under oxidative stress. LC-MS/MS and GFP-trap were performed to study the ShcD phosphorylation status during acute severe oxidative stress. ShcD was found to be phosphorylated at threonine-159 (Thr159) in response to 5 mM H2O2 treatment....
Paper Details
Title
Studying the ShcD and ERK interaction under acute oxidative stress conditions in melanoma cells
Published Date
Jul 1, 2019
Volume
112
Pages
123 - 133
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