Review paper
Portrait of a cancer: mutational signature analyses for cancer diagnostics
Abstract
In the past decade, systematic and comprehensive analyses of cancer genomes have identified cancer driver genes and revealed unprecedented insight into the molecular mechanisms underlying the initiation and progression of cancer. These studies illustrate that although every cancer has a unique genetic make-up, there are only a limited number of mechanisms that shape the mutational landscapes of cancer genomes, as reflected by characteristic...
Paper Details
Title
Portrait of a cancer: mutational signature analyses for cancer diagnostics
Published Date
May 15, 2019
Journal
Volume
19
Issue
1
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