Lime is a new protein linking immunity and metabolism in Drosophila

The proliferation, differentiation and function of immune cells in vertebrates, as well as in the invertebrates, is regulated by distinct signalling pathways and crosstalk with systemic and cellular metabolism. We have identified the Lime gene ( L inking I mmunity and Me tabolism, CG18446) as one such connecting factor, linking hemocyte development with systemic metabolism in Drosophila . Lime is expressed in larval plasmatocytes and the fat...