Review paper
Pathogenesis and Cells of Origin of Barrett's Esophagus
Abstract
In patients with Barrett’s esophagus (BE), metaplastic columnar mucosa containing epithelial cells with gastric and intestinal features replaces esophageal squamous mucosa damaged by gastroesophageal reflux disease. This condition is estimated to affect 5.6% of adults in the United States, and is a major risk factor for esophageal adenocarcinoma. Despite the prevalence and importance of BE, its pathogenesis is incompletely understood and there...
Paper Details
Title
Pathogenesis and Cells of Origin of Barrett's Esophagus
Published Date
Aug 1, 2019
Journal
Volume
157
Issue
2
Pages
349 - 364.e1
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Notes
History