Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits
Abstract
Reward-processing impairment is a common symptomatic dimension of several psychiatric disorders. However, whether the underlying pathological mechanisms are common is unknown. Herein, we asked if the decrease in the n-3 polyunsaturated fatty acid (PUFA) lipid species, consistently described in these pathologies, could underlie reward-processing deficits. We show that reduced n-3 PUFA biostatus in mice leads to selective motivational impairments....
Paper Details
Title
Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits
Published Date
Apr 1, 2020
Journal
Volume
31
Issue
4
Pages
755 - 772.e7
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