Model-based optimization of integrated purification sequences for biopharmaceuticals
Abstract
Finding the best purification process is a challenging task. Recently, mechanistic models that can accelerate the development of chromatographic unit operations, the most important purification units, became widely available. In previous work, several chromatographic models have been linked together to simulate and optimize integrated processes. However, considering only chromatographic steps may lead to a suboptimal process. Consequently, the...
Paper Details
Title
Model-based optimization of integrated purification sequences for biopharmaceuticals
Published Date
Aug 1, 2019
Volume
3
Pages
100025 - 100025
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