Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE

Here, we explore the serum levels of anti-oxidized lipid autoantibodies as well as immune complexes in patients with SLE and determine their correlation with disease. Serum levels of oxidized-LDL immune complexes, autoantibodies to dsDNA, ox-LDL, MDA-LDL, 9-HODE, 13-HODE and POVPC were detected by ELISA in 64 SLE patients and 9 healthy controls. Active SLE patients exhibited increased serum levels of autoantibodies compared to healthy controls,...