Analysis of the duration and extent of the legacy effect in patients with type 2 diabetes: A real-world longitudinal study

To analyze the duration and extent of the legacy effect on diabetic complications in real-world patients with type 2 diabetes. This was a retrospective cohort study. We included the following three cohorts of patients: diabetic retinopathy (DR) (n = 1107), diabetic kidney disease (DKD) (n = 1486), and cardiovascular disease (CVD) (n = 1485). Patients were enrolled from 1995 to 1999 and followed up to 2017. Endpoints were DR incidence, ≥40%...