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Moderate weight change following diabetes diagnosis and 10 year incidence of cardiovascular disease and mortality

Published on May 7, 2019in Diabetologia 7.11
· DOI :10.1007/s00125-019-4886-1
Jean Strelitz (University of Cambridge), Amy L Ahern13
Estimated H-index: 13
(University of Cambridge)
+ 5 AuthorsSimon J. Griffin64
Estimated H-index: 64
(University of Cambridge)
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Abstract
Aims/hypothesis Adults with type 2 diabetes are at high risk of developing cardiovascular disease (CVD). Evidence of the impact of weight loss on incidence of CVD events among adults with diabetes is sparse and conflicting. We assessed weight change in the year following diabetes diagnosis and estimated associations with 10 year incidence of CVD events and all-cause mortality.
  • References (38)
  • Citations (0)
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References38
Newest
Published on Dec 1, 2018in Cardiovascular Diabetology 5.95
Thomas R. Einarson52
Estimated H-index: 52
(U of T: University of Toronto),
Annabel Acs3
Estimated H-index: 3
+ 1 AuthorsUlrik Haagen Panton3
Estimated H-index: 3
(Novo Nordisk)
Background Cardiovascular disease (CVD) is a common comorbidity in type 2 diabetes (T2DM). CVD’s prevalence has been growing over time.
Published on Feb 1, 2018in Value in Health 5.04
Thomas R. Einarson52
Estimated H-index: 52
(U of T: University of Toronto),
Annabel Acs3
Estimated H-index: 3
+ 1 AuthorsUlrik Haagen Panton3
Estimated H-index: 3
(Novo Nordisk)
Abstract Background Cardiovascular diseases (CVDs) constitute major comorbidities in type 2 diabetes mellitus (T2DM), contributing substantially to treatment costs for T2DM. An updated overview of the economic burden of CVD in T2DM has not been presented to date. Objective To systematically review published articles describing the costs associated with treating CVD in people with T2DM. Methods Two reviewers searched MEDLINE, Embase, and abstracts from scientific meetings to identify original res...
Published on Dec 1, 2017in The Lancet 59.10
Michael E. J. Lean76
Estimated H-index: 76
(Glas.: University of Glasgow),
W. S. Leslie14
Estimated H-index: 14
(Glas.: University of Glasgow)
+ 22 AuthorsKieren G. Hollingsworth31
Estimated H-index: 31
(Newcastle University)
Summary Background Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed to assess whether intensive weight management within routine primary care would achieve remission of type 2 diabetes. Methods We did this open-label, cluster-randomised trial (DiRECT) at 49 primary care practices in Scotland and the Tyneside region of England. Practices were randomly assigned (1:1), via a computer-generated list, to provide either a weight management programme (intervention) or be...
Published on Oct 1, 2017in Value in Health 5.04
Annabel Acs3
Estimated H-index: 3
,
Craig Ludwig3
Estimated H-index: 3
+ 2 AuthorsUlrik Haagen Panton3
Estimated H-index: 3
Abstract Background Cardiovascular diseases (CVDs) constitute major comorbidities in type 2 diabetes mellitus (T2DM), contributing substantially to treatment costs for T2DM. An updated overview of the economic burden of CVD in T2DM has not been presented to date. Objective To systematically review published articles describing the costs associated with treating CVD in people with T2DM. Methods Two reviewers searched MEDLINE, Embase, and abstracts from scientific meetings to identify original res...
Published on Jun 1, 2017in Current obesity reports
Donna H. Ryan51
Estimated H-index: 51
(Pennington Biomedical Research Center),
Sarah Ryan Yockey1
Estimated H-index: 1
Purpose of Review One begins to see improvement in glycemic measures and triglycerides with small amounts of weight loss, but with greater levels of weight loss there is even greater improvement. In fact, the relationship between weight loss and glycemia is one that is very close.
Published on Jul 1, 2016in BMJ Open 2.38
Lorna Aucott28
Estimated H-index: 28
(Aberd.: University of Aberdeen),
Sam Philip25
Estimated H-index: 25
(ARI: Aberdeen Royal Infirmary)
+ 3 AuthorsSarah H. Wild57
Estimated H-index: 57
(Edin.: University of Edinburgh)
Objectives To determine weight change patterns in Scottish patients 2 years after diagnosis of type 2 diabetes and to examine these in association with medium-term glycaemic, mortality and cardiovascular outcomes. Setting Using a retrospective cohort design, ethical approval was obtained to link the Scottish diabetes care database to hospital admission and mortality records. Participants 29 316 overweight/obese patients with incident diabetes diagnosed between 2002 and 2006 were identified with ...
Published on Jan 25, 2016in PLOS ONE 2.78
Rasmus Køster-Rasmussen7
Estimated H-index: 7
(UCPH: University of Copenhagen),
Mette Simonsen7
Estimated H-index: 7
+ 3 AuthorsNiels de Fine Olivarius17
Estimated H-index: 17
(UCPH: University of Copenhagen)
Objective This study examined the influence of weight loss on long-term morbidity and mortality in overweight (BMI≥25kg/m2) patients with type 2 diabetes, and tested the hypothesis that therapeutic intentional weight loss supervised by a medical doctor prolongs life and reduces the risk for cardiovascular disease in these patients.
Published on Nov 1, 2015in The Lancet Diabetes & Endocrinology 24.54
Björn Eliasson45
Estimated H-index: 45
(University of Gothenburg),
Vasileios Liakopoulos2
Estimated H-index: 2
(University of Gothenburg)
+ 4 AuthorsSoffia Gudbjörnsdottir39
Estimated H-index: 39
(University of Gothenburg)
Summary Background In patients with diabetes and obesity specifically, no studies have examined mortality after bariatric surgery. We did a nationwide study in Sweden to examine risks of cardiovascular disease and mortality in patients with obesity and diabetes who had undergone bariatric surgery (Roux-en-Y gastric bypass [RYGB]). Methods In this nationwide, matched, observational cohort study, we merged data for patients who had undergone RYGB registered in the Scandinavian Obesity Surgery Regi...
Cited By0
Newest
Published in Cardiovascular Diabetology 5.95
Jean Strelitz (University of Cambridge), Amy L Ahern13
Estimated H-index: 13
(University of Cambridge)
+ -3 AuthorsSimon J. Griffin64
Estimated H-index: 64
(University of Cambridge)
Large changes in health behaviors achieved through intensive lifestyle intervention programs improve cardiovascular disease (CVD) risk factors among adults with type 2 diabetes. However, such interventions are not widely available, and there is limited evidence as to whether changes in behaviors affect risk of CVD events. Among 852 adults with screen-detected type 2 diabetes in the ADDITION-Cambridge study, we assessed changes in diet, physical activity, and alcohol use in the year following dia...