Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart
Abstract
Myocardial dysfunction is commonly associated with accumulation of cardiac lipid droplets (LDs). Perilipin 2 (Plin2) is a LD protein that is involved in LD formation, stability and trafficking events within the cell. Even though Plin2 is highly expressed in the heart, little is known about its role in myocardial lipid storage. A recent report shows that cardiac overexpression of Plin2 result in massive myocardial steatosis suggesting that Plin2...
Paper Details
Title
Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart
Published Date
May 6, 2019
Journal
Volume
9
Issue
1
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