Original paper
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Abstract
Neutrophils are crucial mediators of host defense that are recruited to the central nervous system (CNS) in large numbers during acute bacterial meningitis caused by Streptococcus pneumoniae . Neutrophils release neutrophil extracellular traps (NETs) during infections to trap and kill bacteria. Intact NETs are fibrous structures composed of decondensed DNA and neutrophil-derived antimicrobial proteins. Here we show NETs in the cerebrospinal...
Paper Details
Title
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Published Date
Apr 10, 2019
Journal
Volume
10
Issue
1
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Notes
History