Original paper
Bioproduction of pure, kilobase-scale single-stranded DNA
Abstract
Scalable production of kilobase single-stranded DNA (ssDNA) with sequence control has applications in therapeutics, gene synthesis and sequencing, scaffolded DNA origami, and archival DNA memory storage. Biological production of circular ssDNA (cssDNA) using M13 addresses these needs at low cost. However, one unmet goal is to minimize the essential protein coding regions of the exported DNA while maintaining its infectivity and production purity...
Paper Details
Title
Bioproduction of pure, kilobase-scale single-stranded DNA
Published Date
Apr 16, 2019
Journal
Volume
9
Issue
1
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Notes
History