Original paper
Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity
Abstract
Doxorubicin (DOX) is one of the most widely used anticancer agents. DOX is known for inducing cardiotoxicity, resulting in the long-term development of heart failure. Intravascular delivery of DOX may benefit from the carriage by red blood cells (RBCs), as they can limit the systemic toxicity while delivering the DOX to the tumor. This study proposes a methodology for the synthesis of electrophoretically DOX-loaded red blood cells (RBC-DOX), as...
Paper Details
Title
Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity
Published Date
Jan 1, 2019
Journal
Volume
26
Issue
1
Pages
433 - 442
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Notes
History