Original paper

Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity

Volume: 26, Issue: 1, Pages: 433 - 442
Published: Jan 1, 2019
Abstract
Doxorubicin (DOX) is one of the most widely used anticancer agents. DOX is known for inducing cardiotoxicity, resulting in the long-term development of heart failure. Intravascular delivery of DOX may benefit from the carriage by red blood cells (RBCs), as they can limit the systemic toxicity while delivering the DOX to the tumor. This study proposes a methodology for the synthesis of electrophoretically DOX-loaded red blood cells (RBC-DOX), as...
Paper Details
Title
Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity
Published Date
Jan 1, 2019
Volume
26
Issue
1
Pages
433 - 442
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