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Alfredo Lucas
University of California, San Diego
9Publications
1H-index
2Citations
Publications 9
Newest
#1Alfredo LucasH-Index: 1
Last.Pedro CabralesH-Index: 35
view all 7 authors...
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#1Alfredo Lucas (UCSD: University of California, San Diego)H-Index: 1
#2Kang Wang (UCSD: University of California, San Diego)H-Index: 3
Last.Paul Murphy (UCSD: University of California, San Diego)H-Index: 11
view all 6 authors...
Small-bowel obstruction (SBO) is a common and important disease, for which machine learning tools have yet to be developed. Image annotation is a critical first step for development of such tools. This study assesses whether image annotation by eye tracking is sufficiently accurate and precise to serve as a first step in the development of machine learning tools for detection of SBO on CT. Seven subjects diagnosed with SBO by CT were included in the study. For each subject, an obstructed segment...
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#2Vivek P. JaniH-Index: 3
Last.Pedro CabralesH-Index: 35
view all 8 authors...
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#1Mahantesh S. Navati (Albert Einstein College of Medicine)H-Index: 9
#2Alfredo Lucas (UCSD: University of California, San Diego)H-Index: 1
Last.Pedro Cabrales (UCSD: University of California, San Diego)H-Index: 35
view all 7 authors...
Nitric oxide (NO) is an important factor during an ischemia/reperfusion (I/R) injury. Protective actions of NO during I/R are attributed to antioxidant and anti-inflammatory effects, as well as cell-signaling-based inhibition of nuclear proteins. The therapeutic potential of supplemented NO during I/R is nonetheless uncertain, since peroxynitrite formed from NO near superoxide can be potentially harmful due to NF-κB up-regulation and direct cytotoxicity. This study investigates new technology to...
Source
#1Sarah Gehrke (University of Colorado Denver)H-Index: 4
#2Sarah A. Rice (UAF: University of Alaska Fairbanks)H-Index: 1
Last.Angelo D’Alessandro (University of Colorado Denver)H-Index: 44
view all 11 authors...
Arctic ground squirrels provide a unique model to investigate metabolic responses to hibernation in mammals. During winter months these rodents are exposed to severe hypothermia, prolonged fasting, and hypoxemia. In the light of their role in oxygen transport/off-loading and owing to the absence of nuclei and organelles (and thus de novo protein synthesis capacity), mature red blood cells have evolved metabolic programs to counteract physiological or pathological hypoxemia. However, red blood ce...
Source
#1Alfredo Lucas (UCSD: University of California, San Diego)H-Index: 1
#2John Hermiz (UCSD: University of California, San Diego)H-Index: 3
Last.Vikash Gilja (UCSD: University of California, San Diego)H-Index: 24
view all 6 authors...
Stroke patients are monitored hourly by physicians and nurses in an attempt to better understand their physical state. To quantify the patients’ level of mobility, hourly movement (i.e. motor) assessment scores are performed, which can be taxing and time-consuming for nurses and physicians. In this paper, we attempt to find a correlation between patient motor scores and continuous accelerometer data recorded in subjects who are unilaterally impaired due to stroke. The accelerometers were placed ...
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#1Alfredo Lucas (UCSD: University of California, San Diego)H-Index: 1
#2Dawn Lam (UCSD: University of California, San Diego)H-Index: 1
Last.Pedro Cabrales (UCSD: University of California, San Diego)H-Index: 35
view all 3 authors...
AbstractDoxorubicin (DOX) is one of the most widely used anticancer agents. DOX is known for inducing cardiotoxicity, resulting in the long-term development of heart failure. Intravascular delivery of DOX may benefit from the carriage by red blood cells (RBCs), as they can limit the systemic toxicity while delivering the DOX to the tumor. This study proposes a methodology for the synthesis of electrophoretically DOX-loaded red blood cells (RBC-DOX), as well as the assessment of its antitumorigen...
1 CitationsSource
#1Alfredo Lucas (UCSD: University of California, San Diego)H-Index: 1
#2Alexander T. Williams (UCSD: University of California, San Diego)H-Index: 3
Last.Pedro Cabrales (UCSD: University of California, San Diego)H-Index: 35
view all 3 authors...
This paper implements logistic regression models (LRMs) and feature selection for creating a predictive model for recovery form hemorrhagic shock (HS) with resuscitation using blood in the multiple experimental rat animal protocols. A total of 61 animals were studied across multiple HS experiments, which encompassed two different HS protocols and two resuscitation protocols using blood stored for short periods using five different techniques. Twenty-seven different systemic hemodynamics, cardiac...
Source
#1Vivek P. Jani (UCSD: University of California, San Diego)H-Index: 3
#2Shawn Mailo (UCSD: University of California, San Diego)H-Index: 1
Last.Pedro Cabrales (UCSD: University of California, San Diego)H-Index: 35
view all 6 authors...
In 2013, nearly 15 million units of banked blood were transfused in the United States of America alone. Blood shortages are expected to increase globally. Donated blood is not equal due to differences in quality and deterioration rate. There are no methods to detect time-dependent biochemical and biophysical changes of red blood cells (RBCs) or the deterioration rate of donated RBCs. Nine randomly selected RBC units collected by the San Diego Blood Bank were examined for interdonor variability o...
1 CitationsSource
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