Original paper
DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination
Abstract
Functional antibody genes are often assembled by VDJ recombination and then diversified by somatic hypermutation. Identifying the combination of sourcing germline genes is critical to understand the process of antibody maturation, which may facilitate the diagnostics and rapid generation of human monoclonal antibodies in therapeutics. Despite of successful efforts in V and J fragment assignment, method in D segment tracing remains weak for...
Paper Details
Title
DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination
Published Date
Mar 14, 2019
Journal
Volume
20
Issue
1
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Notes
History