Original paper

Targeting the thioredoxin system as a novel strategy against B‐cell acute lymphoblastic leukemia

Volume: 13, Issue: 5, Pages: 1180 - 1195
Published: Apr 5, 2019
Abstract
B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) is a genetically heterogeneous blood cancer characterized by abnormal expansion of immature B cells. Although intensive chemotherapy provides high cure rates in a majority of patients, subtypes harboring certain genetic lesions, such as MLL rearrangements or BCR‐ABL1 fusion, remain clinically challenging, necessitating a search for other therapeutic approaches. Herein, we aimed to validate...
Paper Details
Title
Targeting the thioredoxin system as a novel strategy against B‐cell acute lymphoblastic leukemia
Published Date
Apr 5, 2019
Volume
13
Issue
5
Pages
1180 - 1195
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