MESENCHYMAL STEM CELLS AND CHONDROCYTE CO - CULTURE PROMOTE CHONDROCYTE MATRIX PRODUCTION IN NORMOXIC CONDITIONS

Articular cartilage is a tissue that shows no capacity for effective spontaneous regeneration. Tissue engineering, as a new important field of regenerative medicine, emerges as potential effective solution for treatment of articular cartilage injuries and defects. The aim of this study was to evaluate the chondrocyte preference of oxygen level for three-dimensional (3D) in vitrochondrogenesis and to test whether the presence of mesenchymal stem...