Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons
Abstract
Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular function of sleep is unknown, and there is no conserved molecular marker to define sleep across phylogeny. Time-lapse imaging of chromosomal markers in single cells of live zebrafish revealed that sleep increases chromosome dynamics in individual neurons but not in two other cell types. Manipulation of sleep, chromosome dynamics, neuronal activity, and DNA...
Paper Details
Title
Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons
Published Date
Mar 5, 2019
Journal
Volume
10
Issue
1
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