Compressed Influenza Vaccination in U.S. Older Adults: A Decision Analysis

Introduction Tradeoffs exist between efforts to increase influenza vaccine uptake, including early season vaccination, and potential decreased vaccine effectiveness if protection wanes during influenza season. U.S. older adults increasingly receive vaccination before October. Influenza illness peaks vary from December to April. Methods A Markov model compared influenza likelihood in older adults with (1) status quo vaccination (August–May) to...