Synchrotron X-Ray Scattering Studies to Determine Structure of Amyloid Beta Interactions with Lipid Membranes

Alzheimer's disease (AD) is the 6th leading cause of death in the United States with more than 5 million people currently diagnosed. The cause of AD remains debated, but one known factor is that the peptide amyloid beta (Aβ) is present at high concentrations in the extracellular space around neuronal cells. Aβ is known to directly interact with neuronal cell membranes, resulting in deadly consequences for the cell such as membrane...