Review paper

Death domain of p75 neurotrophin receptor: a structural perspective on an intracellular signalling hub

Volume: 94, Issue: 4, Pages: 1282 - 1293
Published: Feb 14, 2019
Abstract
The death domain (DD) is a globular protein motif with a signature feature of an all‐helical Greek‐key motif. It is a primary mediator of a variety of biological activities, including apoptosis, cell survival and cytoskeletal changes, which are related to many neurodegenerative diseases, neurotrauma, and cancers. DDs exist in a wide range of signalling proteins including p75 neurotrophin receptor (p75 NTR ), a member of the tumour necrosis...
Paper Details
Title
Death domain of p75 neurotrophin receptor: a structural perspective on an intracellular signalling hub
Published Date
Feb 14, 2019
Volume
94
Issue
4
Pages
1282 - 1293
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