Central role of the β-cell in driving regression of diabetes after liver transplantation in cirrhotic patients

•The mechanisms underlying diabetes regression after liver transplantation are unclear. •Diabetes regressed in ∼2/3 of diabetic patients and developed in <10% of non-diabetic individuals. •Only baseline HbA1c and a family history of diabetes independently predicted regression. •β-cell function governed changes in glucose regulation after liver transplantation. •A sustained improvement of insulin sensitivity accompanied rescue of β-cell function....