Review paper

Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation

Blood21.00
Volume: 133, Issue: 13, Pages: 1427 - 1435
Published: Mar 28, 2019
Abstract
The classical model of hematopoiesis proposes a hierarchy in which a small number of multipotent hematopoietic stem cells (HSCs) maintain all blood lineages by giving rise to progeny that pass through discrete progenitor stages. At each stage, lineage differentiation potential is restricted, coupled with the loss of ability to self-renew. Recently, single-cell approaches have been used to test certain assumptions made by this model, in...
Paper Details
Title
Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation
Published Date
Mar 28, 2019
Journal
Volume
133
Issue
13
Pages
1427 - 1435
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