Epilepsy Gene Therapy Using an Engineered Potassium Channel
Abstract
Refractory focal epilepsy is a devastating disease for which there is frequently no effective treatment. Gene therapy represents a promising alternative, but treating epilepsy in this way involves irreversible changes to brain tissue, so vector design must be carefully optimized to guarantee safety without compromising efficacy. We set out to develop an epilepsy gene therapy vector optimized for clinical translation. The gene encoding the...
Paper Details
Title
Epilepsy Gene Therapy Using an Engineered Potassium Channel
Published Date
Feb 12, 2019
Journal
Volume
39
Issue
16
Pages
3159 - 3169
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