Cross-Sectional Associations of Plasma Per- and Polyfluoroalkyl Substances with Lipid Profile among Pre-Diabetic Adults-Report from the Diabetes Prevention Program

Per- and polyfluoroalkyl substances (PFASs) may interfere with lipid regulation but most previous studies examined occupational cohorts or general populations but not those with high metabolic risks. Among 957 adults in the Diabetes Prevention Program, we measured plasma concentrations of 6 PFASs and lipoproteins at recruitment (1996-1999) and examined their cross-sectional associations using linear regression adjusting for potential confounding...