Review paper
CRISPR–Cas: a tool for cancer research and therapeutics
Abstract
In the past decade, the development of a genome-editing technology mediated by CRISPR has made genetic engineering easier than ever, both in vitro and in vivo. CRISPR systems have enabled important advances in cancer research by accelerating the development of study models or as a tool in genetic screening studies, including those aiming to discover and validate therapeutic targets. In this Review, we discuss these applications as well as new...
Paper Details
Title
CRISPR–Cas: a tool for cancer research and therapeutics
Published Date
Jan 21, 2019
Volume
16
Issue
5
Pages
281 - 295
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