Polygenic Risk Scores in Neurodegenerative Diseases: a Review
Abstract
This review summarizes the current state of the art of polygenic risk scores (PRSs) in the assessment of risk for neurodegenerative diseases. Polygenic risk scores have been used to identify the shared genetic architecture between comorbid complex traits, disease presentations, and disease endophenotypes. The pathological and symptomatologic overlap between neurodegenerative diseases is strikingly high. In some cases, the diagnostic decision is...
Paper Details
Title
Polygenic Risk Scores in Neurodegenerative Diseases: a Review
Published Date
Jan 17, 2019
Volume
7
Issue
1
Pages
22 - 29
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