Proteomic analysis of stratum corneum in Cutaneous T‐Cell Lymphomas and psoriasis

Stratum corneum collected by tape stripping from 10 and 24 subjects with cutaneous T‐cell lymphomas ( CTCL ) or psoriasis, respectively, were compared using quantitative label‐free mass spectrometry analysis. A non‐supervised statistical analysis (Posneg NMF ) based on 352 differentially expressed proteins in both CTCL and psoriasis samples was able to separate the two disease groups and finally able to identify a set of 112 proteins that...