Original paper
Vitamin D-modulated dendritic cells delay lethal graft-versus-host disease through induction of regulatory T cells
Volume: 188, Pages: 103 - 110
Published: Apr 1, 2019
Abstract
Graft-versus-host disease (GVHD) is the most lethal complication after allogeneic bone marrow transplantation (allo-BMT). Current approaches to prevent GVHD rely on donor lymphocyte/T cell depletion or general immunosuppression, leading to opportunistic infections and cancer relapse. Tolerogenic dendritic cells can induce regulatory T cells (Tregs) with the ability to suppress inflammation and prevent transplant rejection, making them an...
Paper Details
Title
Vitamin D-modulated dendritic cells delay lethal graft-versus-host disease through induction of regulatory T cells
Published Date
Apr 1, 2019
Volume
188
Pages
103 - 110
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Notes
History