Original paper
Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms
Abstract
The introduction of next-generation sequencing has broadened the genetic landscape of myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the biological role and clinical impact of most other mutations are not well defined. We interrogated 101 genes in 143 BCR-ABL1-negative MPNs in chronic phase from 2 large institutions. We detected SF3B1 mutations in 15 cases (10%) and set to investigate the clinical, morphologic, and...
Paper Details
Title
Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms
Published Date
Apr 1, 2019
Journal
Volume
86
Pages
1 - 11
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Notes
History