Early and late childhood telomere length predict subclinical atherosclerosis at age 14 yrs. – The CardioCAPS study

Introduction Carotid Intima Media Thickness (CIMT) is a marker of subclinical atherosclerosis, associated with cardiovascular risk in adults. Telomere length (TL) is a marker of cellular ageing. We sought to determine whether telomere length in early childhood and/or at 14-years is associated with CIMT in adolescence, in a community-based cohort study. Methods 118 children had TL measured at mean age 3.6-years and 165 children had TL and CIMT,...