Original paper

Structural heterogeneity ofattCintegron recombination sites revealed by optical tweezers

Volume: 47, Issue: 4, Pages: 1861 - 1870
Published: Dec 19, 2018
Abstract
A predominant tool for adaptation in Gram-negative bacteria is the functional genetic platform called integron. Integrons capture and rearrange promoterless gene cassettes in a unique recombination process involving the recognition of folded single-stranded DNA hairpins-so-called attC sites-with a strong preference for the attC bottom strand. While structural elements have been identified to promote this preference, their mechanistic action...
Paper Details
Title
Structural heterogeneity ofattCintegron recombination sites revealed by optical tweezers
Published Date
Dec 19, 2018
Volume
47
Issue
4
Pages
1861 - 1870
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